From Rte 20, take School Street (at the Weston center traffic light) approx. 0.5 miles south and bear right on Wellesley Street. Continue about 1.0 miles to the museum, on the right, after the Regis College campus. From Rte 30, take Wellesley Street (at the traffic light near Weston High School) approx. 0.4 miles north to the museum, which is on the left. Park in the large parking lot on the right of the driveway just past the museum -- not in the small lot behind the museum.
Or take commuter rail--Framingham-Worcester line to Wellesley Farms -- Schedule here https://mbta.com/schedules/CR-Fitchburg/timetable -- or Fitchburg line to Kendall Green -- schedule here: https://mbta.com/schedules/CR-Worcester/timetable.